StressCovidV1, Main, Exploration, bibRecord, 001280

Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season.

Identifieur interne : 001280 ( Main/Exploration ); précédent : 001279; suivant : 001281

Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season.

Auteurs : Mathias Altmann [Allemagne] ; Lena Fiebig ; Silke Buda ; Rüdiger Von Kries ; Manuel Dehnert ; Walter Haas

Source :

Emerging infectious diseases [ 1080-6059 ] ; 2012.

RBID : pubmed:23092713

Descripteurs français

KwdFr :
- Adolescent, Allemagne, Enfant, Enfant d'âge préscolaire, Facteurs de l'âge, Facteurs de risque, Grippe humaine (histoire), Grippe humaine (épidémiologie), Histoire du 21ème siècle, Humains, Infection croisée (épidémiologie), Nourrisson, Pandémies, Saisons, Sous-type H1N1 du virus de la grippe A, Surveillance de la population, Études prospectives.
MESH :
- histoire : Grippe humaine.
- épidémiologie : Grippe humaine, Infection croisée.
- Adolescent, Allemagne, Enfant, Enfant d'âge préscolaire, Facteurs de l'âge, Facteurs de risque, Histoire du 21ème siècle, Humains, Nourrisson, Pandémies, Saisons, Sous-type H1N1 du virus de la grippe A, Surveillance de la population, Études prospectives.
Wicri :
- geographic : Allemagne.

English descriptors

KwdEn :
- Adolescent, Age Factors, Child, Child, Preschool, Cross Infection (epidemiology), Germany, History, 21st Century, Humans, Infant, Influenza A Virus, H1N1 Subtype, Influenza, Human (epidemiology), Influenza, Human (history), Pandemics, Population Surveillance, Prospective Studies, Risk Factors, Seasons.
MESH :
- geographic : Germany.
- epidemiology : Cross Infection, Influenza, Human.
- history : Influenza, Human.
- Adolescent, Age Factors, Child, Child, Preschool, History, 21st Century, Humans, Infant, Influenza A Virus, H1N1 Subtype, Pandemics, Population Surveillance, Prospective Studies, Risk Factors, Seasons.

Abstract

We conducted a nationwide hospital-based prospective study in Germany of influenza A(H1N1)pdm09 cases among children <15 years of age admitted to pediatric intensive care units and related deaths during the 2009-10 pandemic and the 2010-11 postpandemic influenza seasons. We identified 156 eligible patients: 112 in 2009-10 and 44 in 2010-11. Although a shift to younger patients occurred in 2010-11 (median age 3.2 vs. 5.3 years), infants <1 year of age remained the most affected. Underlying immunosuppression was a risk factor for hospital-acquired infections (p = 0.013), which accounted for 14% of cases. Myocarditis was predictive of death (p = 0.006). Of the 156 case-patients, 17% died; the difference between seasons was not significant (p = 0.473). Our findings stress the challenge of preventing severe postpandemic influenza infection in children and the need to prevent nosocomial transmission of influenza virus, especially in immunosuppressed children.

DOI: 10.3201/eid1811.120719
PubMed: 23092713

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">We conducted a nationwide hospital-based prospective study in Germany of influenza A(H1N1)pdm09 cases among children <15 years of age admitted to pediatric intensive care units and related deaths during the 2009-10 pandemic and the 2010-11 postpandemic influenza seasons. We identified 156 eligible patients: 112 in 2009-10 and 44 in 2010-11. Although a shift to younger patients occurred in 2010-11 (median age 3.2 vs. 5.3 years), infants <1 year of age remained the most affected. Underlying immunosuppression was a risk factor for hospital-acquired infections (p = 0.013), which accounted for 14% of cases. Myocarditis was predictive of death (p = 0.006). Of the 156 case-patients, 17% died; the difference between seasons was not significant (p = 0.473). Our findings stress the challenge of preventing severe postpandemic influenza infection in children and the need to prevent nosocomial transmission of influenza virus, especially in immunosuppressed children.</div>
</front>
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Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season.

Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Stress et Covid
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